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Oliver G Ottmann Selected Research

Stem Cell Transplantation

1/2018Genomic CDKN2A/2B deletions in adult Ph+ ALL are adverse despite allogeneic stem cell transplantation.
2/2014Long-term results of a prospective randomized trial evaluating G-CSF priming in intensive induction chemotherapy followed by autologous stem cell transplantation in elderly patients with acute myeloid leukemia.
4/2007Imatinib combined with mitoxantrone/etoposide and cytarabine is an effective induction therapy for patients with chronic myeloid leukemia in myeloid blast crisis.
7/2005Early molecular response to posttransplantation imatinib determines outcome in MRD+ Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL).

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Oliver G Ottmann Research Topics

Disease

28Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2020 - 01/2002
25Philadelphia Chromosome
01/2020 - 01/2002
20Leukemia
01/2020 - 01/2002
17BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2021 - 03/2002
14Neoplasms (Cancer)
01/2018 - 02/2004
11Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
08/2021 - 10/2003
6Infections
08/2014 - 03/2004
5Hematologic Neoplasms (Hematological Malignancy)
01/2020 - 10/2002
5Residual Neoplasm
01/2017 - 12/2002
4Disease Progression
10/2017 - 03/2002
4Blast Crisis (Blast Phase)
02/2009 - 05/2002
2Essential Thrombocythemia
01/2021 - 09/2015
2Inflammation (Inflammations)
01/2016 - 03/2004
2Carcinogenesis
01/2014 - 01/2013
2Lymphoma (Lymphomas)
01/2014 - 12/2013
2Glioma (Gliomas)
11/2013 - 03/2010
2Cytopenia
09/2006 - 05/2002
2Rheumatoid Arthritis
06/2002 - 01/2002
1Pathologic Complete Response
11/2016
1Graft vs Host Disease (Graft-Versus-Host Disease)
10/2016
1Precursor B-Cell Lymphoblastic Leukemia-Lymphoma (Leukemia, Pre B Cell)
10/2016
1Body Weight (Weight, Body)
09/2015
1Diarrhea
07/2015
1Multiple Myeloma
07/2015
1Nausea
07/2015
1Toxic Optic Neuropathy
07/2015
1Fever (Fevers)
08/2014
1Myelodysplastic Syndromes (Myelodysplastic Syndrome)
08/2011
1Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous)
10/2009
1Hodgkin Disease (Hodgkin's Disease)
10/2009
1Dyspnea (Shortness of Breath)
10/2007
1Neutropenia
07/2007
1Febrile Neutropenia
07/2007
1Leukocytosis (Pleocytosis)
12/2005

Drug/Important Bio-Agent (IBA)

35Imatinib Mesylate (Gleevec)FDA Link
11/2016 - 01/2002
11Tyrosine Kinase InhibitorsIBA
01/2021 - 01/2002
6nilotinibFDA Link
01/2021 - 06/2006
5Phosphotransferases (Kinase)IBA
08/2021 - 01/2003
5Proteins (Proteins, Gene)FDA Link
11/2013 - 10/2002
4Cytarabine (Cytosar-U)FDA LinkGeneric
08/2021 - 01/2004
4Pharmaceutical PreparationsIBA
07/2015 - 05/2002
4bcr-abl Fusion ProteinsIBA
01/2013 - 03/2002
4Valproic Acid (Depakote)FDA LinkGeneric
08/2011 - 12/2005
4Diphosphonates (Bisphosphonates)IBA
08/2005 - 09/2003
3blinatumomabIBA
01/2020 - 12/2012
3Dasatinib (BMS 354825)FDA Link
10/2017 - 03/2010
3CytokinesIBA
10/2016 - 03/2004
3Histone Deacetylase InhibitorsIBA
04/2007 - 04/2004
3Zoledronic Acid (Zometa)FDA Link
08/2005 - 09/2003
3Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
09/2003 - 01/2002
2BI 6727IBA
08/2021 - 08/2014
2imetelstatIBA
01/2021 - 09/2015
2Telomerase (Telomerase Reverse Transcriptase)IBA
01/2021 - 09/2015
2Azacitidine (5 Azacytidine)FDA Link
10/2017 - 08/2011
2Chimeric Antigen ReceptorsIBA
01/2017 - 10/2016
2Granulocyte Colony-Stimulating Factor (G-CSF)IBA
02/2014 - 07/2007
2Histones (Histone)IBA
12/2010 - 03/2006
2Biomarkers (Surrogate Marker)IBA
12/2010 - 05/2008
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
03/2009 - 07/2007
2Tretinoin (Retinoic Acid)FDA LinkGeneric
03/2006 - 12/2005
2Interleukin-18 (Interleukin 18)IBA
03/2004 - 01/2002
1Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
01/2020
1dactolisibIBA
01/2020
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
01/2020
1TOR Serine-Threonine KinasesIBA
01/2020
1T-Cell Antigen Receptors (T-Cell Receptor)IBA
01/2018
1Methotrexate (Mexate)FDA LinkGeneric
11/2016
1Asparaginase (Elspar)FDA Link
11/2016
1Immunoglobulin FragmentsIBA
10/2016
1Thymic Stromal LymphopoietinIBA
01/2016
1Heat-Shock Proteins (Heat-Shock Protein)IBA
07/2015
1Bortezomib (Velcade)FDA Link
07/2015
15- (2,4- dihydroxy- 5- isopropylphenyl)- 4- (4- morpholin- 4- ylmethylphenyl)isoxazole- 3- carboxylic acid ethylamideIBA
07/2015
1Phosphatidylinositols (Phosphatidylinositol)IBA
01/2014
1AntibodiesIBA
12/2013
1HLA Antigens (Human Leukocyte Antigens)IBA
12/2013
1Interleukin-2 (IL2)IBA
12/2013
1MSC1992371AIBA
09/2013
1Aurora KinasesIBA
09/2013
1Polo-Like Kinase 1IBA
08/2012
1moesinIBA
12/2011
1Histone Acetyltransferases (Histone Acetyltransferase)IBA
12/2010
1ErythropoietinFDA Link
10/2010
1Isoleucine (L-Isoleucine)FDA Link
09/2010
1Threonine (L-Threonine)FDA Link
09/2010
1PanobinostatIBA
10/2009
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
10/2007
1CreatinineIBA
10/2007
1Complementary DNA (cDNA)IBA
07/2007
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
07/2007
1Mitoxantrone (Novantrone)FDA LinkGeneric
04/2007
1Etoposide (VP 16)FDA LinkGeneric
04/2007
1Drug CombinationsIBA
10/2006
1fms-Like Tyrosine Kinase 3IBA
03/2006

Therapy/Procedure

24Therapeutics
08/2021 - 01/2002
11Drug Therapy (Chemotherapy)
08/2021 - 10/2003
4Stem Cell Transplantation
01/2018 - 07/2005
2Immunotherapy
01/2018 - 10/2016
2Aftercare (After-Treatment)
03/2006 - 07/2003
1Induction Chemotherapy
02/2014